Detection Strategies for Glycosphingolipids
What are Glycosphingolipids? Glycosphingolipids (GSLs) are complex lipids integral to the structure and function of cell membranes. Composed of a sphingoid base, a fatty acid (forming the ceramide backbone), and one or more carbohydrate residues, GSLs are primarily located in the outer leaflets of the cytoplasmic membrane and within various intracellular membranes of mammalian tissues.…