Detection Strategies for Glycosphingolipids

What are Glycosphingolipids? Glycosphingolipids (GSLs) are complex lipids integral to the structure and function of cell membranes. Composed of a sphingoid base, a fatty acid (forming the ceramide backbone), and one or more carbohydrate residues, GSLs are primarily located in the outer leaflets of the cytoplasmic membrane and within various intracellular membranes of mammalian tissues.…

Sample Processing Methods for Lipidomics Research

Lipids are a class of organic molecules found in nature that are hydrophobic or amphiphilic, insoluble in water but soluble in nonpolar solvents. They are present in most biological systems and serve as the structural material for cell membranes and the secondary source of energy. Lipids also participate in many important cellular functions. Many major…

Glycosylation in Health and Disease

Glycan glycosylation Protein is the executor of life activities. During the study of protein, researchers find that there are many modifications of the protein. Among these modifications, glycosylation modification is quite common, and more than 50% of the proteins found so far have glycosylation modification. Glycan is the sugar part of glycoprotein, including a sugar…

Top-Down Proteomics vs Bottom-Up Proteomics

Protein research is one of the most challenging topics in analytical chemistry. Initial protein research focused on developing techniques capable of isolating and identifying major sequences (or portions) of proteins. Edman degradation of peptide is a revolutionary method to identify the main amino acid sequence of peptide. In addition, the whole sequence of proteins can…

Gene delivery

CD BioSciences offers a variety of plant platforms to construct virus-like particles, including Nicotiana benthamiana, Medicago rativa, Arabidopsis thaliana and Oryza sativa, among others. More about: Gene delivery Gene delivery

PARP Inhibitor Development for Fallopian Cancer

Alfa Cytology is a biotechnology leader focused on pioneering cancer basic research services. The team collaborates meticulously to achieve overarching goals centered on enhancing cancer diagnostics, unveiling new treatment modalities, and discovering novel cancer biomarkers. Alfa Cytology offers bespoke services and dynamic platforms underscored by strong analytical expertise. The services range from genetic analysis, tumor…